Devil's trumpet is toxic to most animals, including cats, dogs, and horses. When the poisonings occur, the outcome can be fatal as the alkaloids inhibit nerve and muscle communication throughout the body including the involuntary digestive system and the brain. Animals that are exposed to Datura metel plant will experience: - Dilated pupils - Anxiety and restlessness - Tachycardia - Increased breathing rate - Constipation - Thirst and urine retention - Lack of coordination and the inability to stand or walk - Hypothermia - Convulsions - Coma Luckily, animal poisonings rarely occur as the plant has a very unpleasant taste and odor. Even though the plant itself has an unpleasant odor and taste, the seeds have a more palatable taste for dogs. If your dog consumes the seeds, a trip to the veterinarian is highly advisable as soon as you can, because the devil's trumpet toxins are fast-acting.