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Is lesser celandine poisonous?
Lesser celandine is a member of the Ranunculace family or the buttercups, which are widely known as poisonous plants. They contain unstable glucoside ranunculin, which transforms into a bitter oily toxin called protoanemomin when the plant is damaged. All parts of the plant contain these toxic compounds. The most common cases of poisoning among humans are caused by intentional consumption of the lesser celandine, considering it is used in traditional medicine as a remedy for ulcers and hemorrhoids. However, there are no clinical trials that support these beneficial effects. The toxic effects of the plant manifest when the remedy is not adequately prepared and dried. Protoanemonin mostly affects the gastrointestinal tract, as it damages the mucous membranes. Certain studies have also shown that lesser celandine poisoning could lead to severe damage of the liver. If the plant sap comes into contact with the skin, it causes itching, rashes and sometimes even blistering.
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