Agave americana, commonly known as the century plant, is native to Mexico but widely distributed due to cultivation for its ornamental value. Across continents, it is cultivated and may be found across various regions in both hemispheres, suggesting a presence far beyond its native range. Century plant has naturalized in many areas and is sometimes thought to be invasive, potentially affecting local ecosystems through its robust growth and reproductive strategies. In certain areas within continents such as Africa, Asia, and Europe, century plant is considered invasive, where it may have an impact on native plant communities and biodiversity.

Century plant's sap contains irritants like calcium oxalate crystals and acrid oils causing minor dermatitis in humans upon skin contact. Century plant's leaves and sap pose mild toxicity to cats and dogs. Ingesting large amounts may cause poisoning symptoms. Pet owners should prevent pets from chewing century plant, and seek immediate veterinary care if poisoning is suspected.