Climbing dayflower has a broad geographic presence, predominantly spanning the tropical and sub-tropical regions of the Americas. Its native range covers substantial areas of these continents, fostering a diverse ecological engagement. In certain regions, climbing dayflower's introduction has led to its consideration as an invasive species, where it may have an impact on local ecosystems. Despite this, the plant's adaptability contributes to its widespread distribution.

Climbing dayflower is a weed that grows in Hawaii and warm climate states such as Texas, Louisiana, and Mississippi. This species is widespread throughout the world's warmer temperate regions in Africa, Asia, and the Pacific in forests, wetlands, marshes, and floodplains. Despite its attractive small blue flowers, it can be difficult to control in a garden setting. It is listed as a noxious weed by the US Department of Agriculture and by the state of Florida. It does not appear on state or national invasive species lists. The weed invades crop fields and competes for nutrients and light. Use hoeing, hand extractions, and herbicides for controlling spread.

The best season for removing climbing dayflower is in early spring or during the rainy season, prior to the weed flowering or setting seeds. This plant tends to flower and spread rapidly, so early intervention is key. Here are some methods to help control this plant: