Perennial wall-rocket is native to Western Asia and Europe but has been introduced to South America, North America, and Australia. This weed often roots in old walls and waste areas in USDA zones 5 to 9. It is recorded as an invasive weed in Australia, Spain, Argentina, the United Kingdom, and the United States. In Australia, the presence of perennial wall-rocket has been linked to lower crop yields of cereal and hay, constituting a threat to local farmers. When necessary, perennial wall-rocket can be removed through the use of chemical herbicides or mechanical methods (such as pulling by hand).