Nipple-fruit, a plant with a notable presence across various major regions, is cultivated and thrives in both its native and introduced ranges. Native to parts of Central and South America, nipple-fruit also has managed to establish itself in various areas of Asia, Africa, the Pacific, and some regions in North America. In particular, it is sometimes thought to be intrusive in certain island ecosystems in the Pacific and Southeast Asia where its presence may have an impact on native species. Despite this, nipple-fruit continues to be cultivated in many areas, reflecting a balance between its horticultural value and ecological considerations.