Annesorhiza requires a balance of sunlight and partial shade, consistent watering while being cautious of overwatering, and well-drained soil with moderate fertility. They thrive in temperate climates and are sensitive to extreme temperatures. Common challenges include root rot, pests such as aphids, and fungal diseases. Seasonally, annesorhiza may need protection from harsh sun or frost, reduced watering in winter, and possible support during flowering in spring and summer.