Brugmansia suaveolens (angel's trumpet) boasts a broad geographical presence, originally flourishing in South America and has since been introduced to various regions across the globe, including parts of Asia, Europe, and Africa. While angel's trumpet is actively cultivated for ornamental purposes, it has also found a foothold outside its native range, sometimes thought to be potentially impactful to local ecosystems. In particular, it may be considered invasive in certain areas where it has the capability to adapt and proliferate in new environments. Despite this, the extent to which angel's trumpet disrupts ecosystems is cautiously noted, suggesting a level of integration that requires ongoing monitoring.

Angel's trumpets are highly toxic to humans, cats, and dogs. All parts, especially leaves and seeds, contain harmful alkaloids. Ingestion can cause serious illness or death, with symptoms like elevated heart rate, pupil dilation, paralysis of smooth muscles, blurred vision, and seizures. Immediate veterinary care is crucial for pets after angel's trumpet ingestion.