Purging croton is a plant species indigenous to tropical regions across Southeast Asia and the Indian Subcontinent. It has become naturalized in parts of Eastern Asia. While native to major regions of Asia, purging croton has also been introduced to other tropical areas, where it has established itself.

Purging croton is a highly toxic tree. All parts are poisonous, especially the fruit. Contact causes skin blisters and dermatitis; eye contact leads to keratoconjunctivitis. Ingestion results in burning sensations, abdominal pain, vomiting, and can lead to dizziness, delirium, convulsions, and death. The toxins are phorbol, phorbol esters, and crotin.

Purging croton is an extremely poisonous weed that poses a threat to forests in both the temperate and tropical world. Though it is not strictly invasive and sometimes even grown purposefully, its spread causes many problems, as it is toxic for fish and mammals, which can drastically affect local ecosystems. Purging croton can grow up to 12 meters tall and thrives in nearly every environment, allowing it to outcompete native species for sunlight and nutrients. Though its poison repels insects, it is a significant carrier of viruses that can threaten nearby plants and animals. Remove manually while wearing gloves and long sleeves, or suppress with herbicides.