In Europe and temperate Asia, oxeye daisy is a native, widespread flowering perennial. It has been introduced into other temperate-zone countries, including the US, Canada, Australia, and New Zealand. It has also been reported to spread further into Asia and high elevation ground in subtropical regions.
Although it has been naturalized for a long time in the countries listed above, oxeye daisy is considered invasive because it is a prolific seed producer and also spreads via rhizomes. A mature plant can produce up to 26,000 seeds which can remain viable for 40 years and are easily dispersed by animals, vehicles, water, and contaminated agricultural seeds. It is often a weed of naturally poor soils, degraded pastures, and roadsides. Oxeye daisy can reduce the quality of the pasture as cattle won't eat it, and a dense infestation can suppress native plants and cause soil issues in sensitive ecosystems.