Greater knapweed is indigenous to parts of the Western Palaearctic zone, flourishing in grasslands and meadows. It has also adapted beyond its native range, becoming established in parts of Northern Europe and North America, where it is sometimes found in cultivated settings. This expansion illustrates greater knapweed's ability to thrive in both its endemic regions and introduced territories.

Greater knapweed originates from Europe and Asia. It is viewed as a weed because of its robust growth and ability to dominate an area, thereby potentially suppressing other plant life. The plant's prolific seed production and long germination period allow it to spread aggressively and make it difficult to control. Its long taproots enable it to survive in various soil types and conditions, from well-drained to clay soil. As it prefers to grow in full sun, it could potentially occupy large areas of your garden, leaving little room for your preferred plants. What makes it rather harmful is that it can outcompete native plants, potentially leading to decreased biodiversity in your garden or nearby natural habitats. When growing greater knapweed in your garden, watch for a significant increase in its presence. The plant's main means of dispersal is by seeds, which can be carried by the wind or attached to animals passing by. Monitoring the plant's growth and seed development could help manage its spread.

The ideal time to address the spread of greater knapweed is early spring, before it blooms and sets seeds. At this stage, the plants are more vulnerable and can be managed more easily.