Asthma-plant, a well-adapted species, enjoys a broad distribution spanning multiple regions. Native to Central and South America, asthma-plant has been introduced across various continents, including Asia, Africa, Oceania, and sporadically in North America. In its introduced range, asthma-plant is sometimes thought to be of concern, particularly in certain areas of Africa where its proliferation may have an impact on local ecosystems. Despite this, asthma-plant is not typically cultivated, and its ecological influence remains a subject of observation rather than alarm.

Asthma-plant is mildly toxic to children, causing nausea, vomiting, and diarrhea if raw leaves are ingested. The leaves contain E. hirta extract, with toxicity occurring at around 5g per 1kg of body weight. Although safe for adults, care must be taken around children.

Originating from South America, asthma-plant has spread in tropical and subtropical regions worldwide, including countries of Africa, Asia, and Oceania. Of European countries, it has been recorded in Russia. It is a potent weed because of its rapid spread; flowers appear when the plant is very young and the seeds sprout almost instantly after maturation, with no dormancy period. That is why asthma-plant's population can increase rapidly over a short period. The plant's sap contains latex that is an irritant, causing contact dermatitis especially problematic for the eyes, and limited-severity poisoning if ingested. Symptoms are digestive and include nausea and vomiting. Protective gloves should be worn when removing the plant.

The best season to remove asthma-plant is during the dry season, specifically before it begins to flower and disperse seeds. Below are the effective methods for controlling this plant: