Caesarweed has a widespread presence primarily across various tropical and subtropical regions. This species is indigenous to parts of Asia, Africa, South America, and Central America, flourishing in a range of climates within these major areas. It has also established itself in certain Pacific and Caribbean islands, as well as in parts of South America, where its presence is sometimes thought to be invasive. In these ecosystems, caesarweed may have an impact, due to its vigorous growth and adaptability.

Caesarweed originates from the tropical regions of Asia, Africa, and the Americas. Often considered a weed, it is notorious for its high levels of adaptability and reproductive ability which enables it to spread swiftly, infesting lawns and gardens. One plant can produce about 4500 seeds annually, effectively contributing to its invasiveness. Its harmfulness stems from its robust nature and ability to outcompete native plant species, thereby disturbing the balance of the ecosystem. Dense clusters of caesarweed can form a thick mat, inhibiting the growth of other plants and affecting the overall aesthetics of gardens. The plant primarily spreads through its seeds, which are dispersed by wind, water, and human activity, often attaching to clothing or animal fur, ensuring widespread distribution.

The best season for removal of Urena lobata, or caesarweed as commonly known, is during the early stages of spring, before it reaches the state of flowering. It should be done to prevent the spread of seeds and further proliferation of this invasive species. Here are some methods of controlling or removing caesarweed: